Uneven skin color may be caused by physiological factors or pathological factors, and common diseases include simple furuncle, eczema and ringworm. Symptoms can be improved through general treatment and medication. 1. Physiological factors: some people may be affected by heredity and other factors, born with uneven skin color, usually does not affect the health, no need for treatment. 2. Pathologic factors: (1) Furfura simplex: also known as white furfura, it is a kind of hypopigmented spot that occurs on the facial skin. In terms of treatment, it is mainly symptomatic to give moisturizing as well as supplemental multivitamin treatment, such as topical Vitamin E urea cream, oral multivitamin tablets and so on. (2) Eczema: an inflammatory skin disease caused by a variety of factors, with many clinical manifestations. The main treatment is to give anti-allergic medication, such as topical dinexed cream, oral levocetirizine capsules and so on. (3) Ringworm: a disease caused by localized skin infection with ringworm bacteria, which may also be manifested as uneven skin color in the clinic. In terms of treatment, the main target is to give antifungal drug treatment, such as ketoconazole cream, miconazole nitrate cream and so on. Due to the different causes of the disease, the treatment program is different, the specific circumstances need to follow the doctor’s prescription medication.