For people suffering from kidney disease, diabetes, hyperuricemia, immune system disorders and other diseases, if the treatment is not effective, with the development of the disease, it is easy to progress to uremia.
1. Kidney disease: for example, people with a family history of hereditary kidney disease are more likely than normal people to suffer from chronic kidney disease, such as hereditary nephritis. Chronic kidney disease can easily lead to uremia. There are also patients with primary glomerular disease, which may cause renal fibrosis and thus uremia if it is not effectively treated for a long time.
2. Diabetes mellitus: For patients with poor blood sugar control, it may cause related complications, such as diabetic nephropathy, which may lead to chronic kidney injury and secondary uremia.
3. Hyperuricemia: it can be divided into acute hyperuricemia nephropathy and chronic hyperuricemia nephropathy. In the acute stage, a large amount of uric acid is excreted through the kidneys, blocking the renal tubules, and the glomerular filtration rate decreases sharply. Chronic phase can be manifested as a decrease in tubular concentration function, which in turn affects glomerular filtration function, leading to a decrease in creatinine clearance and ultimately leading to uremia.
4. Immune system diseases: such as lupus nephritis, IgA nephropathy and so on. It is caused by the accumulation of immune complexes in the kidneys, which in turn affects renal function, and long-term illness may also lead to uremia.
Uremia may also be caused by other reasons, it is recommended that patients go to the regular hospital in time, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.