If the pulp is painful after encountering hot and cold stimulation, if it is the symptom of pulpitis, it is suggested that the patient should take broad-spectrum antibiotics, such as cephalosporin, erythromycin, roxithromycin, etc., and then cooperate with anti-anaerobic bacteria drugs, such as metronidazole, ornidazole, tinidazole, etc. Patients are suggested to go to the stomatology department of hospital for clear diagnosis to determine the cause, and the nature of pain should be judged, if it is a transient pain caused by hot and cold stimulation, it may be a tooth caries, and the pain problem can be solved by removing the decaying matter and filling the cavity, no medicine is needed. If the decay has reached the nerve or the pain cannot be relieved by hot and cold stimulation, it may be the symptom of inflammation of dental pulp, and root canal treatment is needed to solve the disease completely, and then with the treatment of medicine, the disease can be cured faster and the pain can be relieved for the patient.