Lonicera japonica and honeysuckle are different in terms of flavor and attribution, efficacy and main treatment. 1. Lonicera japonica is sweet in flavor and cold in nature, belonging to lung and stomach meridian; honeysuckle is sweet in flavor and cold in nature, belonging to lung, heart and stomach meridian. 2. Lonicera has the effect of clearing away heat and toxins (clearing away heat and toxins in the body), dredging the wind and opening up the channels; honeysuckle has the effect of clearing away heat and toxins, and evacuating wind-heat. 3. Lonicera japonica is mainly used for the treatment of fever of warm diseases, rheumatism-heat paralysis (often manifested as burning, pain, redness and swelling of joints and muscles), joints, redness, swelling and heat pain, pyrexia and dysentery (dysentery caused by feeling heat and poison and blood in stools), carbuncle sores and ulcers and so on. It is also forbidden for those who have deficiency of spleen and stomach (weak and cold spleen and stomach), and those who have more than one diarrhea. Honeysuckle is mainly used for the treatment of carbuncle and furuncle (mostly occurring on the limbs or face, small in shape with deep roots, as hard as nails), fever and blood dysentery, external wind-heat, sore throat and other evidence. Its adverse reactions and contraindications are not yet clear. If similar symptoms occur, it is recommended to consult a Chinese medicine practitioner for an interview, diagnosis and treatment, prescription and standardized treatment, and do not self-medicate.