High prostate specific antigen 5.24ng/ml may be caused by benign prostate diseases, prostate cancer and other disease factors, or by physiological stimulation of the prostate gland. 1. Benign prostate diseases: If the patient has symptoms such as prostatitis and prostate hyperplasia, prostate specific antigen may also be elevated. 2. Prostate cancer: prostate-specific antigen is an important screening index for prostate cancer, which is an important and reliable tumor marker for diagnosing prostate cancer, evaluating the effects of various treatments and predicting the prognosis. When the prostate-specific antigen is elevated, it suggests the possibility of prostate cancer and further diagnosis and treatment is recommended. 3. Physical stimulation: For example, catheterization, prostate massage, prostate puncture and other operations may stimulate the prostate gland, which may lead to high prostate-specific antigen. There are many reasons for high prostate-specific antigen, so it is recommended that patients go to the hospital, complete the relevant examinations, and then further treatment after a clear diagnosis of the cause of the disease, so as to avoid delaying the condition.