The role of the hepatitis B vaccine is to protect the liver by preventing the invasion of the hepatitis B virus, and the role of the BCG vaccine is to prevent tuberculosis infection. Therefore, newborns must receive the hepatitis B vaccine and BCG within 24 hours of birth. Secondly, if the baby is in the period of sickness, he/she can not go for the vaccination for a while and can be vaccinated when he/she is well. In addition, the hepatitis B vaccine is valid for 5-7 years and care must be taken to test the antibody level regularly after the injection because the antibody level produced after the vaccination will gradually decrease with time, so it is recommended that a booster once in three years after the immunization will be more effective.