Five years of repeated hospitalization for heart failure often suggests that heart failure has progressed to refractory end-stage heart failure, at which time the goal of treatment is to try to alleviate clinical symptoms, improve quality of life, improve long-term prognosis, and reduce the rate of death and hospitalization. It usually includes general and pharmacologic treatment. General treatment includes lifestyle management, which requires patients to maintain stable emotions, standardize medication, and follow up regularly. Clinical symptoms can also be reduced by a low-salt diet. Patients should limit physical activity and rest in bed when their condition is unstable. Timely elimination of triggers, a common trigger for acute attacks of heart failure is infection, avoiding respiratory infections can effectively reduce heart failure attacks. Drug therapy to cardiotonic diuretic, control the heart rate, reduce the burden on the heart, improve clinical symptoms, commonly used drugs include furosemide, spironolactone, captopril, valsartan, bisoprolol and so on. Comprehensive treatment of heart failure requires the participation of physicians and patients, and patients need to implement healthy life management, and standardized medication under the guidance of physicians, and regular follow-up.