Taking antibiotics may kill the normal vaginal flora and lead to the destruction of the vaginal self-cleaning ability, so it is easy to develop vaginal mycobacterial infections. Mycobacterial infection of the vagina is mainly caused by Pseudomonas vulvae vaginitis. The main clinical manifestations are itching, burning pain, painful intercourse, and painful urination of the vulva, and some patients may experience increased vaginal discharge. Painful urination is mainly due to irritation of the edematous vulva and vestibule by urine. The vaginal discharge is characterized by a thick, white, curd-like or pea-like discharge. The main treatment is to eliminate the cause, stop using broad-spectrum antibiotics, change underwear regularly, avoid wearing tight underwear, maintain local cleanliness and avoid sharing sanitary ware, and use clotrimazole vaginally.