Why do I need chemotherapy for breast cancer?

  Why do breast cancer patients need chemotherapy?  Because chemotherapy can prevent cancer recurrence and metastasis, especially for breast cancer patients with metastatic lymph nodes, poor grading and high malignancy, which are prone to recurrence and metastasis, so chemotherapy is needed.  However, many patients worry that chemotherapy has an impact on immunity, and the side effects of chemotherapy are unbearable, and their fear of chemotherapy is much greater than their fear of surgery. There is now very clear evidence (50-year post-operative breast cancer follow-up study) that patients who have chemotherapy survive significantly longer than those who do not have chemotherapy. Although the quality of life is affected during the short period of chemotherapy, and the adverse effects of chemotherapy may cause nausea, vomiting, hair loss, etc., in the long run, the benefits of chemotherapy are far greater than the possible recurrence and metastasis, and it is worth the effort.  Breast cancer is a systemic disease, and chemotherapy is an important treatment for breast cancer that is no less important than surgery in some ways.  But do not all breast cancer patients need post-operative chemotherapy?  The answer is no, not every breast cancer patient needs chemotherapy, only patients with indications for chemotherapy (such as lymph node metastasis, high malignancy, poor differentiation, etc.) need chemotherapy: First, reliable pathological examination results, immunohistochemical examination results are complete, based on which the patient is judged whether to do chemotherapy; Second, the patient’s Second, the patient’s liver and kidney function, blood routine, urine routine, electrocardiogram, etc., some special chemotherapy may also need to do further evaluation of the patient’s heart function, the need to do echocardiography and so on. Chemotherapy can only be administered to patients who meet these conditions.  After the patient’s ability to undergo chemotherapy is determined, the doctor will develop a personalized chemotherapy regimen based on the patient’s specific situation (chemotherapy regimens vary from person to person and will not be identical).  For example, the commonly used regimen of epi-adriamycin combined with cyclophosphamide is usually 4 courses of treatment with an interval of 3 weeks; if epi-adriamycin is combined with cyclophosphamide and paclitaxel, there are usually 8 courses of treatment, but the time interval between courses may be different – 3 weeks for general chemotherapy, 2 weeks for intensive chemotherapy. In this way, there are 8 courses of chemotherapy, and the duration of intensive chemotherapy will be significantly shortened. The choice of conventional chemotherapy or intensive chemotherapy is a professional issue and should be decided by the doctor based on the condition and the patient’s physical condition.