Does stage II breast cancer with 1 lymph node metastasis not require radiotherapy after chemotherapy with modified radical surgery? There are controversies about whether radiotherapy is needed for 1-3 lymph node metastases, and the principle used to be that the decision should be based on a combination of factors such as the patient’s age, pathological findings, immunohistochemical results, and the degree of lymph node clearance, etc. In 2014, it was reported in the literature that radiotherapy is beneficial for this group of patients, but it will take time and more research results to see if the view is widely accepted. What are the indications for radiotherapy after modified radical mastectomy for breast cancer? T3-4 (primary tumor > >5cm) pN2 (≥4 axillary lymph node metastases) pN1 (1-3 axillary lymph node metastases) combined with high risk factors (age, receptor, number of lymph nodes, etc.) Do I still need radiotherapy after modified radical surgery + prosthesis implantation with only the nipple preserved after surgery? Will radiotherapy affect the prosthesis? The need for radiotherapy after surgery is based on the disease and pathology results. The effect on the prosthesis will be minimal. What is the plan of radiotherapy after modified radical surgery for breast cancer? Is it better to use whole breast radiotherapy or stereotactic radiotherapy? Are there any special requirements in terms of equipment and technology? If radiotherapy is needed after radical surgery, conventional radiotherapy can be used to achieve good results at a lower cost. The exact site of irradiation is determined by the disease. If breast-conserving surgery is performed, radiotherapy is required for the vast majority of cases after surgery. If whole breast radiotherapy is performed, conventional radiotherapy, 3D conformal radiotherapy and intensity modulated radiotherapy are the most commonly used radiotherapy techniques. How long is the best time to have radiotherapy after modified radical surgery for breast cancer? It is best to do it within 3 months, and if adjuvant chemotherapy is needed, the maximum time should not exceed 6-8 months. Is it possible to have radiotherapy and chemotherapy at the same time? If radiation and chemotherapy are interspersed, will the interval between chemotherapy sessions exceed 21 days and will it affect the treatment? Generally, it is not recommended to administer radiotherapy and chemotherapy at the same time. If the interval between chemotherapy is too long, it will still have an effect. Do I need to have PET-CT before and after radiation therapy for breast cancer? No. PET/CT is not mandatory, it is optional depending on the need of the disease.