Total bilirubin 24.30 μmol/L may be due to cirrhosis, or it may be caused by physiologic factors, other liver diseases, blood system diseases and so on. 1. Cirrhosis: patients with cirrhosis may have obvious hepatocellular damage, abnormal liver function, and the liver is unable to convert total bilirubin into direct bilirubin and indirect bilirubin, thus causing high total bilirubin. 2. Physiological factors: most common in newborn babies, mainly caused by neonatal jaundice, usually in the first 2 to 3 days of life will appear in the skin sclera yellow staining phenomenon, but will be gradually relieved on its own. 3. Other liver diseases: such as chronic active hepatitis, viral hepatitis, etc., can lead to abnormal liver function and cause high total bilirubin. 4. Hematological diseases: hemolytic diseases are mostly considered, which often cause high bilirubin. Total bilirubin 24.30μmol/L may also be caused by other reasons, it is recommended to cooperate with the doctor to do further examination, clear diagnosis and early treatment.