Patient: Description of the condition (time of onset, main symptoms, hospital visited, etc.): Biopsy results: (12 degrees of the cervix, cervical canal) chronic inflammation of the mucosa, focal squamous intraepithelial neoplasia grade 2. (3 6 9) Cervical tissue with small focal squamous epithelial lesions of mild severity. Do I need a laparotomy or a conization procedure? Are there any risks? Is the surgery painful? Will it have any effect on future fertility? Tan Lifeng, Department of Gynecology, Zibo Third People’s Hospital: Cervical conization includes LEEP conization and cold knife conization, whether to use LEEP or cold knife depends on the severity of the disease and the doctor’s ability to handle both procedures. Currently, LEEP is preferred for the treatment of high-grade precancerous cervical lesions because it has significantly fewer intraoperative and postoperative complications than cold knife, while cold knife is gradually being marginalized. Based on the information you have provided about your disease, if you are an infertile patient, a cautious and strictly observed follow-up should be preferred. If you are a patient without fertility requirements, you may opt for LEEP cervical conization, but the procedure needs to be done by a colposcopist under colposcopic instruction. The procedure is not very painful, but has potential negative effects on future pregnancies, including preterm labor, premature rupture of membranes, and a double risk of low birth weight. Patient: Dr. Tan, thank you for your analysis. I would like to specify my situation. I was tested for the condition of my cervix this time because I went to Changsha Provincial Maternity Hospital for IVF,. Now the doctor wants me to go for the Lipo knife surgery, I don’t know if this surgery and the cervical conization you mentioned are through one surgery, if not agree a surgery, then how exactly is this condition of mine suitable for treatment? I don’t have any children yet, but my left fallopian tube is completely blocked and my right fallopian tube has fluid, but it is not serious. Thank you. Tan Lifeng, Department of Gynecology, Zibo Third People’s Hospital: Because CIN2 has a large percentage of spontaneous decline, if the lesion is small, biopsy will stimulate the body’s immunity to accelerate its decline. Because the cause is a viral infection, no drugs can be treated, but the virus is self-limiting. What you need to do is to exercise, relax and improve your immunity to accelerate its decline. At the same time, prohibit sexual intercourse for one month, and then repeat TCT, HPV (Hc-2 method is recommended) and colposcopy to see the results before deciding on the next treatment plan, and if necessary, LEEP conization.