Growth hormone pituitary tumor, mention this tumor, you can think of some very peculiar face, we know Mu Tiezhu, right, is suffering from acromegaly so extraordinarily tall, generally with gigantism and dwarfism common. Growth hormone tumor is a rare disease, the proportion of pituitary tumor is according to the previous data, according to the proportion of microadenoma found now, less than 0.1% is a chronic disabling disease, need active treatment, growth hormone tumor found when most of the adenoma is already a large adenoma. Although most growth hormone tumors are benign, local infiltration is more frequent, and surgery is not easy to cut cleanly.
Therefore, growth hormone pituitary tumors should be treated as soon as they are detected, usually by measuring hormone levels, magnetic resonance imaging, and growth hormone suppression tests. Treatment should be done as soon as it is identified.
Treatment with growth inhibitors is effective in 70% of patients with GH, resulting in a 30% reduction in tumor size; 50% of patients can improve almost all clinical symptoms.
We recommend that preoperative injection of Zanlon can be used before surgery for giant adenoma, with tumor shrinkage or growth hormone decline, and then surgery, and postoperative reapplication of surgery is more ideal.
In addition, bromocriptan can reduce GH level and shrink the tumor by 10%-15%. Other drugs such as carte blanche are also effective.
Some main matters of surgery: Because the distant endangerment of acromegaly to more organ enlargement changes, the irreversibility of such changes can affect organ function, even to a fatal extent, early treatment is still recommended.
We have found that patients with limbomegaly sometimes have difficulty in tracheal intubation and obstructed breathing, so special attention should be paid to this aspect.
In addition, for the judgment of surgical effect, growth hormone should drop immediately after tumor removal, and sometimes those who do not drop or even still at the upper limit of normal value should be told to pay attention and inject growth inhibitor intramuscularly if necessary. This kind of recurrence rate is larger.
Some people often ask when the patient’s face can be changed back after the surgery. The answer is of course No. The patient has grown into a human being, how can it shrink back? Generally, the patient will not continue to develop abnormally. Sometimes, the limbs will feel relaxed and may become more proportional in the future.