The pain in the toenail may be caused by the following two reasons: 1. It may be a local accidental kick or a heavy object crushed, resulting in local subcutaneous capillary rupture, bleeding and swelling, pain, can be applied externally to reduce swelling and pain, blood circulation and stasis of the salve or ointment, such as local swelling can be relieved after the elimination of symptoms. If the pain is very severe, you can take oral non-steroidal anti-inflammatory drugs for pain relief and symptomatic treatment. If you’ve got a toe that’s restricted in movement, you must consider the possibility of a fracture and go to the hospital for a local X-ray to rule it out. 2, the appearance of nail fungus, usually the nail edge of the nail groove will appear soft tissue swelling, serious local pus will also appear, you can apply a local disinfectant solution, such as iodophor, alcohol and other disinfectant solution. In addition, oral anti-infective drugs, such as cephalosporin and clindamycin, are commonly used to relieve the pain after the local infection is eliminated. However, if the nail infection is not eliminated after repeated conservative treatment, the nail must be removed after local anesthesia and thoroughly cleared to relieve the underlying cause.