The skull is a very important organ in the human body, a hard barrier that protects the brain, head and face, as well as an important guarantee of a smooth operating environment within the skull. Therefore, if a skull defect occurs, it should be treated in a timely manner. Cranial defects should be repaired as soon as possible at the right time. Generally, after about three months of recovery from emergency treatment, the defect can be repaired. Cranial repair is now a relatively routine procedure in neurosurgery, and technically it is not a big problem, but mainly depends on the quality of the repair material. Currently, the titanium mesh material used in most hospitals has some less than ideal problems, such as rejection caused by titanium mesh exposure, such as a variety of discomforts, such as postoperative patients are sensitive to heat and cold, such as affecting the postoperative CT and MRI examinations, and so on. Currently, our team is using advanced polyetheretherketone PEEK material for cranial bone repair, which has become a new favorite in the cranial bone repair industry due to its excellent properties that are almost comparable to the human cranium and can achieve very ideal cranial bone repair results. Clinically, the application of this material has also achieved great success.