In patients with cranial defects, when the defect is small and located under the temporal or occipital muscles, no significant complications usually occur. If the defect is large, it often leads to deformity of the head, significant headache, dizziness, nausea, vomiting, and memory loss, mild cognitive impairment, inattention, and may even induce traumatic epilepsy. Secondly, as the disease progresses, it may lead to brain tissue edema and brain tissue bulging at the site of the cranial defect, and it may cause compression of the surrounding brain tissue, resulting in lack of blood and oxygen to the surrounding brain tissue, causing neurological dysfunction and even cranial nerve loss. In the case of cranial defects in children, the size of the defect may increase as the skull grows and the brain tissue develops. In addition, the edges of the defect may turn outward, resulting in local deformity, which is also very influential, so it is necessary to treat the skull defect if it exists. Therefore, for patients with cranial defects, if there are no obvious contraindications to surgery should choose to perform cranial repair at an early stage. At present, the most commonly used material is peek material, also called polyether ether ketone material, which is similar to skull in elasticity, hardness, and thermal conductivity, and has the best histocompatibility among the repair materials; and it has no micro-shadowing on X-ray and MRI, which does not affect MRI and CT after repair, and is a relatively safe and mainstream material. After the patient’s cranial bone is repaired, the defect can disappear, so that the above complications can be avoided and the patient can recover as soon as possible.