It is possible to have sex while taking metronidazole for H. pylori. H. pylori infection is one of the most common chronic bacterial infections in humans, and H. pylori infection can cause chronic gastric, duodenal, and gastric cancer. H. pylori is mainly transmitted through the oral-oral and fecal-oral routes, with the oral-oral route being the most common. Kissing each other during sex is unavoidable, but for patients with H. pylori infection, it can increase the risk of H. pylori transmission. Therefore, patients with H. pylori infection should avoid kissing each other as much as possible. For patients with H. pylori, the diet should be mainly light and easy to digest, with less spicy, stimulating and greasy food. If the body is diagnosed with H. pylori infection, it should cooperate with the doctor to carry out anti-H. pylori treatment. During the treatment period, patients need to visit the doctor regularly for gastroscopy and other examinations, and take medication as prescribed by the doctor.