Liver S6 segmental cysts refer to the presence of cysts in segment 6 of the liver, i.e., the lower part of the posterior lobe of the right liver. During an abdominal CT examination, the liver is divided into five lobes and eight segments to make it easier to identify the site of the lesion. The five lobes and eight segments are mainly divided into lobes and segments based on the portal and hepatic veins within the liver. Hepatic S6 cysts refer to the presence of cysts in the lower part of the posterior lobe of the right liver. Generally speaking, liver S6 cyst is a benign lesion of the liver and it is recommended to go to the hospital for regular checkups, if there is no abnormality, it does not need to be treated. If the cyst gradually increases in size, compresses the local liver and affects liver function, surgical resection is recommended. In addition, patients should pay attention to a light diet, avoid spicy and stimulating food, reduce the burden on the liver, moderate exercise, improve the body’s immunity.