Ibuprofen and levofloxacin can generally be taken together. The main ingredients of ibuprofen extended-release capsules are ibuprofen, sodium carboxymethyl starch, dimethylsilicone oil and so on, and the main ingredient of levofloxacin tablets is levofloxacin, both of them can be taken at the same time, there will be no adverse drug reaction between the ingredients, and it is recommended that they can be taken after meals, and they should be used under the advice and guidance of doctors. Ibuprofen belongs to the antipyretic and analgesic anti-inflammatory drugs, mainly used for the treatment of joint pain, headache, toothache, muscle pain, dysmenorrhea, nerve pain, etc. It can also treat fever caused by colds and flu, but it can not eliminate the inflammation, and it may cause irritation to the mucous membranes of the gastrointestinal tract. Levofloxacin is an antibacterial drug, which can be used to treat infectious diseases of the respiratory system, urinary system, etc. Levofloxacin can also irritate the gastrointestinal tract, leading to abdominal pain and diarrhea, vomiting and other adverse reactions. Therefore, when using ibuprofen and levofloxacin, it is important to use them wisely under the advice and guidance of a doctor.