Gallbladder wall roughness diameter 0.8cm may be gallbladder polyps, cholecystitis or gallbladder tumors lead to thickening of the gallbladder wall, need to be further examined to clarify the symptoms, early detection and early treatment. Gallbladder wall roughness is the ultrasound description of the gallbladder wall, the normal thickness of the gallbladder wall is 1~2mm, if the gallbladder wall is thickened and irregular, it may be caused by gallbladder polyps or cholecystitis, but it can’t be ruled out that it is caused by the gallbladder tumor, it is recommended to do CT enhancement examination or MRI scanning, to clarify the symptoms. At present, the wall of gallbladder is already thicker, which meets the indication of cholecystectomy, and it is recommended to remove it through laparoscopic cholecystectomy to avoid disease progression, which may lead to gallbladder cancer. If the wall of gallbladder is thickened and hairy, it is recommended to go to the hospital in time and follow the medical advice.