Patients with SLE are most commonly women of childbearing age, and many patients have recently been asking about when they can become pregnant. Female SLE patients need to meet the following conditions before pregnancy can be considered: 1. the disease remains stable for at least six months; 2. the equivalent dose of glucocorticoids is less than 15mg of prednisone per day; 3. the quantitative urinary protein excretion is less than 0.5g in twenty-four hours; 4. there is no important organ damage; 5. the immunosuppressants such as cyclophosphamide, methotrexate, ralginate, mycophenolate, etc. are stopped for at least six months; 6. For patients taking Leflunomide, it is recommended to stop the drug clearance treatment first and then stop the drug for at least six months before considering pregnancy. Lupus patients with the following conditions are contraindicated for pregnancy: 1. severe pulmonary hypertension with estimated pulmonary artery systolic pressure greater than 50 mmHg or clinical symptoms of pulmonary hypertension; 2. severe restrictive lung lesions with forceful lung volume (FVC) less than 1 liter; 3. cardiac insufficiency; 4. chronic renal insufficiency with blood creatinine greater than 2.8 mg/dl; 5. severe previous pre-eclampsia or HELLP syndrome that cannot be controlled even after aspirin and heparin treatment; 6. Stroke within the past six months; 7. Severe lupus disease activity within the past six months.