Hard acne on the face generally refers to acne, accompanied by pain may be inflammatory papules, cysts, nodules and other skin lesions, which can be improved by general treatment and medication. 1. General treatment: For patients with painful acne on the face, they need to pay attention to personal hygiene and reduce the intake of high-sugar diet and dairy products. You can use warm water to clean your face, and try to avoid staying up all night and having a disturbed lifestyle. 2. medication: patients can use topical fusidic acid cream, clindamycin gel and other antibiotics, with anti-inflammatory and bactericidal effect, can be combined with benzoyl peroxide gel and other drugs, to help the disease recovery. Patients can also take oral medications such as minocycline and isotretinoin, which can reduce inflammation and inhibit acne and Propionibacterium acnes. There are many ways to improve the pain of acne on the face, and it is recommended that patients go to the hospital and cooperate with the doctor to standardize the treatment. All of the above drugs should be used in accordance with the doctor’s instructions, do not self-medication, in order to avoid adverse reactions.