Taking nifedipine controlled-release tablets to measure the blood pressure is always high, may be the dose taken does not reach the effect of lowering blood pressure, or the insensitivity to the antihypertensive drug is caused. Clinically, nifedipine controlled-release tablets belong to dihydropyridine calcium antagonists. After taking it, it can reduce the extracellular calcium ions into the vascular smooth muscle cells, thus reducing the diastolic response of the resistance vessels, and can play a rapid role in lowering blood pressure. If the blood pressure does not decrease after taking the drug, it may be due to the dose of the drug is too low or the drug is not sensitive to the antihypertensive drug. You can increase the dosage of the drug under the guidance of your doctor or change to other drugs or combine with other drugs for treatment. For example, hydrochlorothiazide, metoprolol, enalapril and other drugs can reduce the extracellular volume, reduce peripheral vascular resistance, as well as inhibit myocardial contractility and slow down the heart rate, so as to play a role in lowering blood pressure. Usually the drug causes dizziness, headache, anxiety, tachycardia, edema, constipation, nausea, vomiting and other discomforts. The drug is contraindicated in people who are allergic to the components of the drug. Drivers and operators may experience fatigue, dizziness and other discomforts after taking the drug, so it should be used with caution. Pregnant and lactating women should use the drug under medical supervision. If your blood pressure is still high after taking nifedipine controlled-release tablets, it is recommended to consult a cardiovascular medicine department in time and adjust the medication after the doctor’s comprehensive assessment of your condition.