Sobriety headaches are difficult to treat by drinking more water, inducing vomiting, and using painkillers (ibuprofen, etc.). 1. Drink more water. After waking up with a headache, it is recommended that the patient can drink more water to promote the body’s alcohol discharge and reduce the symptoms of headache. 2. Emetic. The headache after waking up is mainly caused by the stimulating effect of alcohol. By inducing vomiting, the remaining alcohol in the stomach will be discharged, reducing the amount of alcohol in the body and alleviating the headache and other symptoms. 3. Use pain medication. If the headache is serious, you can also use painkillers such as ibuprofen and nimesulide under the guidance of a doctor. If the headache persists after waking up from alcohol, it is recommended that the patient can go to the emergency room of the hospital for treatment.