Menopausal dryness can be treated with erythromycin as an adjunctive medication that acts as an antibacterial and anti-inflammatory agent. Clinical treatment of postmenopausal vaginal dryness of the main drugs for estrogen drugs, such as combining estrogen cream. Patients should use the medication reasonably under the guidance of the doctor. Erythromycin is a bacteriostatic drug that can treat various infections caused by sensitive bacteria. Postmenopausal vaginal dryness may cause symptoms such as mild contusion or dermatophytosis, in which case erythromycin may be used. Vaginal dryness after menopause is usually caused by relatively low estrogen levels, vaginal and urinary tract atrophy, and decreased secretions. It is often treated with estrogen-based medications, such as conjugated estrogen creams. Combined estrogen cream is a mixture of various estrogens and is mainly used to treat atrophic vaginitis and vulvar dryness. Adverse effects of conjugated estrogen cream include symptoms such as breakthrough or spotting bleeding, breast swelling and pain, endometrial hyperplasia, nausea and vomiting, diarrhea and abdominal pain, vertigo, arthralgia, altered libido, edema, alopecia, angioneurotic edema, and allergic skin reactions. In addition, it is contraindicated in patients who are allergic to the components of the drug combined with estrogen cream, in patients with confirmed or suspected pregnancy, in patients who experience abnormal bleeding from the reproductive tract, breast cancer, suffering from estrogen-dependent neoplastic organisms, venous thromboembolism, thromboembolic disorders, hepatic impairment, hemianopsia or total blindness due to vasculopathy of the eye or diplopia. If you need to treat postmenopausal vaginal dryness or use erythromycin drugs, it is recommended that you consult a professional doctor and follow the doctor’s instructions for standardized treatment, not blindly self-medication.