Thyroid nodules can be treated with ablation, but the indications for ablation need to be met under a doctor’s supervision. Thyroid nodules are a common thyroid disease. Patients who develop thyroid nodules can be reviewed regularly if the nodules have no obvious symptoms and there are no changes in thyroid function. If the nodules cause pressure symptoms, or cause changes in thyroid function, they can be treated with medication or surgery. Surgical treatment can choose ablation treatment. Ablation refers to the method of directly destroying or dissolving the nodules by using physical or chemical and complex processes involving physicochemical and biological reactions, after the location and nature of the nodules are clarified and the nodules are accurately hit by percutaneous puncture or ultrasound focusing under image guidance. The advantages of ablation are short time, small damage, fast recovery, no scar, etc. However, if the nodule is large, usually with more contents, then the use of thyroid ablation for treatment is very likely to lead to incomplete ablation of the nodule, and multiple nodules are not suitable for thyroid ablation treatment. Therefore, if thyroid nodules are large and multiple, it is recommended to go to the hospital to improve the thyroid ultrasound to assess the risk of nodules, and if it is difficult to characterize them, it is also necessary to further improve the thyroid fine-needle aspiration biopsy to assess the benignity of the nodules; if it suggests that malignancy is highly likely to occur, it is advisable to carry out surgical treatment as soon as possible. It is recommended that patients with thyroid nodules seek prompt medical attention.