Swelling after diabetic foot surgery may be a normal reaction after surgery, or it may be caused by infection, combined diabetic nephropathy, etc. According to the reason, it is necessary to take treatments such as lowering sugar, diuresis, surgery and so on. 1. Normal postoperative reaction: As the lymph and blood vessels around the lower limbs may be damaged during the surgery, resulting in poor venous return, and then there will be swelling all the time after the surgery, which is a normal reaction after the surgery. Vasoactive drugs can be applied to protect blood vessels and improve blood circulation, which is conducive to the absorption of edema. 2. Infection: postoperative swelling of diabetic foot may also be caused by secondary infection, patients need to use appropriate antibiotic drugs under the guidance of the doctor. 3. Diabetic nephropathy: If the patient himself is also combined with chronic kidney disease, can also lead to postoperative swelling of the lower extremities. Patients need to follow the doctor’s instructions to use furosemide and other diuretics, as well as acarbose, insulin and other hypoglycemic drugs. Those who are more seriously ill need to take peritoneal dialysis, hemodialysis and other renal replacement therapy, or take kidney transplantation. It is recommended that patients who have been swollen after diabetic foot surgery should go to the hospital for consultation to clarify the specific cause and then treat accordingly.