Glutamine aminotransferase is high for the following reasons: First, chronic viral hepatitis, especially with a long history of disease, repeated delays can lead to damage to the liver cell membrane, transamination, deamination metabolic abnormalities, and laboratory tests will show an increase in transaminases, the patient will also have significant liver pain, fatigue, decreased appetite, especially hate fried foods, but also jaundice, should be actively liver protection, anti-viral symptomatic treatment. Secondly, for malignant tumors occurring in the liver, specifically primary liver cancer and metastatic liver cancer, the typical symptoms are pain in the liver area, weight loss, and abnormal enzymatic metabolism, which is also a manifestation of decreased liver function. Patients diagnosed at an early stage should actively choose surgical treatment, and the later stage can also be controlled by interventional therapy and chemotherapy.