The main difference between Hepatitis B major triple positive and minor triple positive lab tests is e antigen positive or negative. Hepatitis B triple positive refers to hepatitis B surface antigen positive, e antigen positive, core antibody positive, these three positive indicates that it is hepatitis B triple positive, the virus replication is more active, whether it is infectious need to test the quantitative hepatitis B virus HBV-DNA, whether it is necessary to test the function of the liver. Hepatitis B minor triple positive refers to positive surface antigen, positive e antibody and positive core antibody. Hepatitis B minor triple positive indicates that the virus replication is not active, whether it is infectious also need to test the hepatitis B virus HBV-DNA quantification, whether it needs treatment need to test the function of the liver, liver ultrasound and the elasticity of the liver measurement.