Generally the sequelae of prostate radiotherapy will improve after finishing radiotherapy and most of them can return to normal. Sequelae of prostate radiotherapy may include systemic reaction, local skin and mucous membrane reaction, rectal reaction and so on. 1. Systemic reaction: It is manifested as dysfunction of the body, such as loss of appetite, mental fatigue, weakness, nausea and vomiting, and bloating after eating, etc. Generally, it takes about two weeks after radiotherapy. Generally, it can disappear in about two weeks after the end of radiotherapy. 2. Local skin and mucous membrane reaction: it can be manifested as skin itching, pigmentation, eczema and blisters at irradiation site, which can be ulcerated in severe cases. Mucous membrane reaction is mainly redness and swelling of oral mucous membrane, congestion, decrease of secretion, dryness of mouth, which can be seen as obvious congestion and edema of oral mucous membrane in severe cases, formation of ulcers and pain, and in severe cases, there can be vesicular eruption, hemorrhage, pus-like secretion, severe pain, and occasional fever. This situation can be used to rehabilitate new liquid gargle and other symptomatic treatment, can quickly return to normal. 3. Rectal reaction: radiation therapy can cause proctitis, resulting in bleeding, ulceration, perforation of the rectal mucosa. You can choose hemostatic drugs, such as thrombin, with mesalazine enema auxiliary treatment, can return to normal. Sequelae of radiotherapy, after a period of time or treatment, generally can be returned to normal, no need to worry too much, pay attention to keep a relaxed mood.