Thyroid nodule 4a can be injected with the new crown vaccine. Simple thyroid nodules are generally not a contraindication to vaccination, but when thyroid function tests reveal significant abnormalities in thyroid function such as hyperthyroidism or hypothyroidism, it is recommended that the new crown vaccine be postponed. Thyroid nodule 4a refers to the color ultrasound for the classification of thyroid nodules, is generally not a contraindication to the new crown vaccination, if the patient does not have uncomfortable symptoms, in the stabilization period of the disease, can be vaccinated with the new crown vaccine. If the patient’s thyroid function is abnormal, such as hyperthyroidism or hypothyroidism, or the patient’s resistance is poor, the patient is in the acute stage of the disease, it is recommended that the new crown vaccine be postponed, and then consider vaccination with the new crown vaccine after the condition is stabilized. It is recommended that patients with thyroid 4a nodules consult their doctor before receiving the vaccine to avoid affecting the effectiveness of the vaccine or the recovery of the disease.