A white blood cell count of 1.61 × 10⁹/L after chemotherapy suggests the presence of third-degree myelosuppression, which is a more serious condition but can usually be effectively corrected by timely intervention. Chemotherapy is a common treatment for malignant tumors, and myelosuppression is one of the most frequent adverse effects of chemotherapy, which can lead to a decrease in the number of peripheral blood cells, with a decrease in the number of white blood cells being more common. Myelosuppression can be categorized into 0 to 4 degrees according to the degree of blood cell decline, and a white blood cell count in the range of 1.0 to 1.9 × 10⁹/L is 3 degrees, which is a more severe degree. Intervention must be given at this point, and injection of recombinant human granulocyte colony-stimulating factor is recommended to effectively improve the reduced white blood cell count, and blood tests should be performed regularly during use. The preparation may cause adverse reactions such as fever, bone pain, rash, etc. It is contraindicated in people who are allergic to its components and those with severe hepatic, renal, cardiac and pulmonary dysfunction. It is recommended to avoid going to crowded places, and the living environment should be well sanitized and disinfected to prevent infection, and protective isolation and other measures should be taken when necessary.