Lumbar vertebral hyperplasia generally refers to lumbar vertebral bone hyperplasia, patients need to follow the doctor’s instructions for drug treatment, general measures, etc., and if necessary, also need to carry out surgical treatment. 1. Medication: Usually, patients need to use non-steroidal anti-inflammatory and analgesic drugs such as celecoxib, diclofenac, meloxicam, etc., and if they have acute pain episodes, they need to use opioid drugs such as codeine and tramadol, so as to alleviate the symptoms. 2. General measures: patients usually need to pay more attention to rest, and timely correction of bad habits, to avoid sedentary, standing for a long time. Patients also need to actively adjust the diet to ensure adequate nutritional intake, and obese people also need to control their weight. At the same time, patients can also wear elastic waist, appropriate restriction of lumbar activity, is conducive to alleviate the symptoms, but should not be worn for a long time. 3. Surgical treatment: If the patient’s condition is more serious, or the non-surgical treatment is ineffective, it is necessary to choose to carry out total laminectomy, posterior total laminectomy intervertebral implant fusion internal fixation under the guidance of the doctor. It is recommended that patients with lumbar spondylolisthesis actively cooperate with the doctor for targeted treatment to avoid delaying the condition.