In our practice, we often encounter patients with severe heart valve disease who, due to various factors (financial constraints, fear of cardiac surgery, lack of medical knowledge, or even inappropriate guidance from some internists), delay the best time for surgery and have a very poor quality of life, often with a life expectancy of less than one year, before coming to the hospital. For such patients, surgical procedures are extremely risky and have poor long-term outcomes, and some patients are even lost to surgery. Therefore, patients with heart valve disease should be seen promptly in a major hospital cardiac surgery department for systematic consultation, careful evaluation of the timing of surgery, and appropriate treatment. Never allow mild valvular disease to progress to severe valvular disease. Criteria for severe heart valve disease 1, oversized giant left ventricle Left ventricular short-axis end-diastolic internal diameter (LVEDD) > 70 mm, left ventricular short-axis end-systolic internal diameter (LVESD) > 5O mm, EF < 0.5, FS < 0.25, and cardiothoracic ratio > 0.70. 2, small left ventricle Left ventricular end-diastolic volume index (EDVI) ≤ 60 ml/m2 , myocardial weight index (LVWI) ≤ 70g/m2 , suggesting left ventricular atrophy. 3, cardiac cachexia cardiac insufficiency, with endocrine, metabolic, nutritional, coagulation mechanisms and other series of disorders. Cardiac function grade III – IV, less than 85% of standard body weight, hepatomegaly, ascites, cardiothoracic ratio of 0.80 or more, and moderate or higher organ insufficiency of liver, kidney and lung.