1.Anti-coagulants and their use As the contact between artificial valve and blood can easily cause platelet coagulation and formation of thrombus, insufficient anticoagulation can easily cause thromboembolism and other evils, and excessive anticoagulation can lead to hemorrhage, therefore, a very important part after valve replacement is proper anticoagulation. Warfarin: once a day, keep the prothrombin time (PT) 18-36 seconds, or international normalized ratio (INR) 1.5-3.0, when there is bleeding from trauma, bleeding gums or subcutaneous bleeding, stop the medication of the day, and check the PT in time. avoid applying blood activating and stasis-relieving drugs at the same time. After discharge, check PT at 1 week, 2 weeks, 1 month, 3 months, and 6 months until adjusted to a stable dose of warfarin, which may be checked every 3 to 4 months. Start tapering the dose the day after each menstrual period, and then begin resuming the original dose after the menstrual bleeding period. Sauerkraut, carrots, cauliflower and spinach will affect the efficacy of warfarin and should be eaten sparingly. 2.Maintenance of cardiac function medication Digoxin: 0.5-1 tablet/dose once daily for 1 to 3 months or longer. Discontinue when pulse <70 beats/min. Diuretics: hydrochlorothiazide 25-50 mg/dose 1-3 times daily for 1 to 3 months or longer. Ambrisentan 20-40 mg/dose 1-3 times daily for 1 to 3 months or longer. Must be taken when coughing while lying down, coughing up white foamy sputum, abdominal distension, and swelling of both lower extremities occur. You can adjust the dosage and duration of the medication yourself, and in severe cases prescribe Fosamax (tachyphylaxis tablets). Captopril: 12.5-25mg/dose twice a day, suitable for patients with big heart and high blood pressure, long-term use can improve heart function. Betalucil: 6.25-25 mg/dose twice daily, suitable for patients with rapid atrial fibrillation (heart rate over 100 beats/minute) and large heart and high blood pressure. 3.In the event of cold and fever, cough, cough pus sputum, timely intravenous application of antibiotics. 4.After valve replacement surgery generally need to rest for 3-6 months, during the rest period, you can take a walk, light housework activities, should gradually increase the amount of activity, in order not to feel tired to the extent. 5, review After valve replacement surgery, although the patient's symptoms have been significantly improved, but in order to maintain good cardiac function, to maintain the normal operation of the artificial valve, must adhere to regular follow-up, and keep in touch with the doctor, in order to facilitate the timely detection of problems, timely treatment.