I. General internal medicine treatment 1, limit physical activity. 2.Prevent upper respiratory tract infection and infective endocarditis, use antibiotics for 2-3 days before and after tooth extraction, surgery. 3.Check whether there is any rheumatic fever activity, if so, anti-rheumatic treatment should be given. Second, the treatment of comorbidities 1, heart failure. 2.Atrial fibrillation, flutter, resuscitation. 3.Infective endocarditis. 4, embolization, vasodilator drugs + anticoagulation. Third, interventional therapy Percutaneous balloon catheter valve expansion molding; suitable for simple mitral stenosis, moderate stenosis, valve area 0, 8-30px2, no obvious closure insufficiency, no atrial fibrillation and thrombus; it is a catheter with a balloon through the blood vessels to the narrow valve opening, filling the balloon one by one, expanding the valve opening. The advantage of this method is that the valve can be dilated without surgery, but it is blind, so it is only suitable for simple valve stenosis or valve damage is not serious, there is no thrombus in the atrium of the patient. Surgical treatment (a) mitral valve separation, the indications are the same as above. (B) Valve replacement, suitable for joint valve disease or combined mitral valve closure insufficiency; valve calcification, funnel-type stenosis; mitral valve stenosis after the separation of the restenosis. For the treatment of heart valve disease in patients with severe valve damage who are no longer able to undergo valvuloplasty, it is necessary to remove the original valve and replace it with a biologic or mechanical valve. (c) Valvuloplasty, which is a relatively difficult procedure to repair a damaged valve to restore its full on/off function, has many benefits for the patient. Firstly, the valve is repaired under direct visualization to achieve the best repair effect; secondly, the lifelong anticoagulation problem after valve replacement is avoided. This method is mainly suitable for stenosis or closure insufficiency where the valve itself is in good shape, such as mitral tendon cable rupture, enlarged annulus, and valvular cleft. The dosage and administration of the above medications are subject to medical advice. For patients who need surgery, delay is generally not recommended. The longer the delay the worse the cardiac function will become by then, the higher the risk of surgery, and the more expensive it will be, with the possibility of losing the surgery in the end.