Pain is an unpleasant subjective sensory and emotional experience associated with tissue damage or potential tissue damage, and is a complex physiological and psychological activity. When various injurious stimuli act on the organism to a certain extent, they can cause the tissues in the damaged area to release some analgesic substances, such as histamine, bradykinin, 5-hydroxytryptamine, acetylcholine, H+, K+, prostaglandins, etc. These substances act on the nociceptors in the skin and other tissues to produce nociceptive impulses, and rapidly afferent neural conduction to the cremasteric medulla, which passes through the cremasteric medullary thalamic tracts and the cremasteric medullary reticulation structures upward and to the thalamus, which then projects to the cerebral cortex to cause pain sensation. If the acute pain is not timely and effective management, structural changes can occur in the central and local, transformed into chronic pain, different parts of the pain characteristics, onset time, pain level, accompanied by different symptoms, but also accompanied by increased blood pressure, increased heart rate, sweating, end cold, loss of appetite, lack of concentration, can not work normally. So body pain must not be tolerated.