Inflammation of the root of the tongue may be caused by the presence of bacterial or fungal infection or local irritants. Antibacterial treatment and antitoxic treatment such as removing local irritants can relieve the inflammation of the root of the tongue as soon as possible, as follows. 1. Bacterial or fungal infection: chlorhexidine gluconate solution, povidone-iodine gargle, ciprofloxacin solution gargle, or cediriodine tablets, lysergic acid tablets, etc. can be used. Drugs should be used under the guidance of a doctor. 2. Local irritating factors: including residual roots, residual crowns, bad restorations and other irritating factors, should be adjusted to grind the sharp tips of the teeth in the oral cavity, remove the bad restorations, the residual roots, residual crowns for the full crown restoration, or extracted after the use of fixed partial denture or implant prosthesis restoration. There may be other reasons for the inflammation of the tongue root, it is recommended to go to the hospital in time, after clarifying the cause of the disease for targeted treatment.