Parkinson’s disease is a common neurological condition that affects middle-aged and elderly people, mainly due to the loss of dopaminergic neurons in the substantia nigra of the brain. The main symptoms are slowing of movement, tremor, muscle stiffness and postural balance disorders. Other symptoms include increasingly small writing, dull expressions, and monotonous and low-pitched speech. Although Parkinson’s disease does not directly lead to death, it will seriously affect the patient’s daily life and reduce the quality of life. Zhang Yuqing, Department of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University The medication for Parkinson’s disease, such as dobutamine (Medoxibar) and carbidopa (Xanax), has a good effect on controlling the patient’s symptoms, and the medication has a “honeymoon period” of about 3 to 5 years. However, as the disease progresses, the efficacy of the medications will gradually decrease, the duration of each medication will become shorter and shorter, the symptoms will fluctuate, and the medications will cause “dance-like” movements (what we call “anomia”), or severe gastrointestinal reactions, etc. At this stage, surgery should be considered. Surgery can be divided into destructive surgery and deep brain electrical stimulation (DBS, also known as pacemaker surgery), which has fewer adverse effects, is safe, reversible and adjustable. The surgical procedure of DBS involves the implantation of stimulation electrodes into the nucleus accumbens of the brain (thalamic nucleus basalis), which are connected by subcutaneous wires to a stimulation generator (battery) implanted under the skin in the chest. The entire device is buried under the skin, and the incision heals without interfering with activities, bathing, etc. After the surgery, the doctor can adjust the stimulation parameters according to the severity of the disease. the DBS procedure has good long-term results and most patients can moderately reduce the drug dosage and improve adverse drug reactions. Therefore, DBS is particularly suitable for patients with high drug side effects, poor treatment results, uncontrollable symptom fluctuations and “isokinetic disorders”. What you see here is a diagram of a DBS, where the entire device is buried under the skin and does not interfere with bathing.