Vitamin B6 is a water-soluble vitamin that is more commonly used in clinical practice and can participate in coenzyme metabolism, thus helping the body to carry out a more normal metabolism of sugar, protein and fat, but it is not vitamin B6 that can inhibit seborrhea secretion. It is true that there are many clinical patients with seborrheic dermatitis whose pathogenesis is related to vitamin B deficiency, but vitamin B supplementation is to help patients regulate the body’s overall metabolic level, not to treat seborrheic dermatitis with vitamin B6 alone. Because the cause of seborrheic dermatitis is also directly related to poor lifestyle habits, as well as fungal colonization, impaired skin barrier, and personal constitution.