Intradural tumors are primary or secondary tumors that occur in the spinal cord and surrounding tissues such as the dura mater, nerve roots, fat and blood vessels. According to the relationship between the tumor and the spinal cord and spinal membrane, they are classified as intraspinal tumors, extramedullary subdural tumors and extradural tumors. According to pathological classification, intraspinal tumors are mostly gliomas, ventricular meningiomas and cavernous hemangiomas; extramedullary subdural tumors are mainly nerve sheath tumors and chordomas; and extradural tumors are mainly lipomas, metastatic tumors, hemangiomas, nerve sheath tumors and so on. Main clinical manifestations (1) Nerve root compression symptoms: manifested as stabbing, cutting or burning pain. The pain is distributed along the nerve root and may radiate to distant places. Coughing, defecation, sneezing or exertion may aggravate the pain. The pain is often severe when lying down and relieved after sitting up and moving around, and some patients show a girdling sensation in the chest and waist. Nerve root compression neuralgia is a common irritation symptom of posterior root compression, especially in extramedullary tumors, and when the anterior root is involved, there may be no root pain but muscle weakness of the corresponding segment, muscle fascicle fibrillation, muscular atrophy and leg reflexes retardation or disappearance. (2) Sensory impairment: patients may show that they cannot perceive the hot water when washing hands or feet, and they do not know the pain when they are stabbed by needles, which is the decrease or disappearance of pain and temperature sensation of the contralateral side of the body below the damaged plane when the spinal cord is compressed. In the early stage of intramedullary tumor, there is segmental bilateral or unilateral pain and temperature sensation loss and tactile sensation preservation of sensory separation phenomenon. (3) Locomotor disorders: manifested as weakness of arms and legs, inability to grasp objects firmly, unsteady walking, etc., which is the manifestation of spinal cord compression. (4) Urinary and faecal disorders: intramedullary tumors appear earlier, and extramedullary tumors often occur at a later stage. In addition, the skin below the damaged area is dry, pale, with excessive or little sweating. (1) Lumbar puncture cerebrospinal fluid examination: it can understand the degree of patency of the spinal canal in order to roughly determine the possibility of tumor, and it can also test the protein and cell number, if there is a separation phenomenon, it suggests the possibility of tumor. (2) X-ray film of spine: it can understand the degree of destruction of vertebrae, such as destruction, thinning and deformation of arch root; widening of intervertebral spacing and enlargement of intervertebral foramen; destruction of posterior edge of vertebral body, depression, and enlargement of anterior and posterior diameters of vertebral canal; speckled calcified foci in the vertebral canal, and paraspinal mass, etc. It suggests the possibility of tumor. (3) CT examination: The location of the tumor can be determined, especially for vertebral bone destructive lesions, and enhancement scanning and three-dimensional reconstruction of the spine are needed when necessary. (4) MRI examination: MRI is the safest and most convenient means to diagnose intraspinal tumors, which can accurately show the segment where the lesion is located, the relationship between the lesion and the spinal cord and dura mater, and the changes of the adjacent subarachnoid space, extradural space and bone, and also make a preliminary diagnosis of the nature of the lesion. (5) PET-CT examination: if patients suspect intradural metastatic tumor, they can receive whole body PET-CT scan, which is easy to find the primary lesion. Main treatment methods 1. Surgical treatment: including tumor resection and palliative surgery (e.g. spinal decompression surgery), most of the extramedullary tumors are feasible to be surgically resected, especially neurofibroma and chordoma with high rate of total resection and really low recurrence rate, which is possible to reach a cure. Due to the application of MRI and the development of microsurgery, the total surgical resection rate and efficacy of intramedullary tumors have also been significantly improved. Therefore, for benign and low malignant tumors, total resection should be strived for; for lipoma, subtotal resection or most of the resection should be performed; for highly malignant tumors, partial resection should be performed, so as to achieve the purpose of reducing the symptoms of spinal cord compression and improving the function of spinal cord. Radiotherapy: For glioma, sarcoma and metastatic tumor which are not easy to be treated by surgery, radiotherapy should be chosen, and radiotherapy can also be used as a supplementary treatment after resection of the tumor. Chemotherapy: chemotherapy can be added to spinal cord glioma and intraspinal metastatic tumor. Prevention and precautions 1. Low back pain is the early manifestation of most spinal cord lesions, such as herniated intervertebral disc, lumbar muscle strain, spinal stenosis, etc., which can be cured by acupuncture, physiotherapy, massage, cupping and other methods of motherland medicine, but intradural tumors are not suitable to be treated with the above methods, which not only have poor effect, but also may cause adverse consequences, therefore, we should not treat the symptoms of low back pain blindly when we have low back pain and we should consult a regular hospital. Therefore, when we have symptoms of low back and leg pain, we should not treat them blindly, but must go to regular hospitals for consultation, and then consider the above methods of treatment after ruling out the tumor. 2.If there is sensory dysfunction, we need to pay attention to the prevention of burns and pressure sores.