How do intraspinal tumors form? Who is prone to get them?

Intravertebral tumors are divided into two categories: primary and secondary. Primary intradural tumors are tumors of the spinal cord, neurovascular, membranous and adipose tissues and bony structures located in the spinal canal, which are important components of central nervous system tumors; while secondary intradural tumors mainly refer to systemic malignant tumors metastasizing to the spinal canal via the blood route or brain parenchymal tumors planted, disseminated and metastasized to the spinal canal via the cerebrospinal fluid route. The incidence rate is 1/6-1/7 of brain tumors, about 2.5/100,000 people. Intraspinal tumors can occur at any age, with peak incidence between 20 and 50 years old, 19% in children, and a slightly higher incidence in men than in women. They are classified clinically as intramedullary, extramedullary subdural and extradural tumors according to their relationship with the spinal cord and dura mater. The tumors can occur in any segment of the spine, with the most occurring in the thoracic segment, accounting for about half of the cases, the cervical segment accounting for about 1/4, and the rest in the lumbar medullary segment and cauda equina.