[Authors] Long Houqing; Liu Shaoyu; Chen Jian; Li Fobao; Liao Weiming; Shen Jingnan; Wan Yong; [Abstract] Objective To observe the clinical and imaging characteristics and surgical efficacy of benign intraspinal tumors. Methods We reviewed the clinical data of 129 cases of benign intravertebral canal tumors that were surgically resected and pathologically confirmed. There were 92 males and 37 females, aged 16-72 years, with an average of 42.9 years. The main symptoms were localized pain, thoracic and abdominal girdling sensation, radicular symptoms, cone-bundle sign or cauda equina symptoms. Due to the location of the tumor, the progression of the tumor was from lower to higher or from higher to lower with the course of the disease. 129 cases of X-ray, 121 cases of MRI, 107 cases of vertebral canal angiography, 92 cases of CT (CTM) examination. There were 109 cases of complete resection, 18 cases of major resection, and 2 cases of simple decompression of the spinal canal with biopsy. Results: This group accounted for 94.7% of the cases of intravertebral tumors in the same period, and the positive rates of X-ray, CTM and MRI were 52.7%, 93.6% and 100%, respectively. Postoperative follow-up ranged from 6 to 107 months, with an average of 39.1 months. There were 93 cases of symptom disappearance, 25 cases of significant improvement of neurological function, 7 cases of no change, and 4 cases of aggravation after surgery. There were 21 cases of recurrence and 17 cases of reoperation, of which 14 cases showed functional improvement. Pathologically, neurofibromas, nerve sheath tumors, ventricular meningiomas, chordomas, lipomas, ganglion cell tumors, astrocytomas, hemangiomas and intravertebral cysts were found in 89% of cases in cervicothoracic region and 11% in lumbosacral region. Conclusion: The performance of benign intravertebral tumors varied greatly according to the site, segment and disease stage, and MRI was the best imaging method to make a clear diagnosis and guide the surgery. The results of surgical resection were satisfactory, and the postoperative recurrence rate was low. Incomplete resection of the tumor was the main cause of recurrence. Long Houqing, Department of Spine Surgery, East Hospital, The First Affiliated Hospital of Sun Yat-sen University, China.