A slight pain in the heart from time to time may be caused by a variety of diseases, such as angina pectoris, arrhythmia, intercostal neuralgia, etc., according to the different situations need to improve the lifestyle, the application of medications as prescribed by the doctor, such as aspirin, simvastatin, isosorbide mononitrate, metoprolol, acyclovir, carbamazepine, pregabalin and so on, or placement of a cardiac stent, radiofrequency ablation surgical treatment. 1. Angina pectoris: coronary artery stenosis, intravascular plaque instability caused by paroxysmal anterior heart pain and other angina pectoris symptoms, can follow the doctor’s instructions for oral drug therapy, such as aspirin, simvastatin, isosorbide mononitrate, and so on. If the condition is serious, the pain time is prolonged or the interval time becomes shorter, the coronary angiography should be carried out in time, if necessary, the feasibility of cardiac stenting treatment. 2. Arrhythmia: common arrhythmias are ventricular premature beats, atrial premature beats, etc. Patients feel a sudden tightness in the precordial area, palpitations or pain, short time, do ECG can be seen as a preperiod contraction, first of all, can be treated by improving the way of life, such as a light diet, abstaining from smoking and alcohol, pay attention to rest, avoid emotional excitement, etc., if the patient’s symptoms are obvious, can be followed by the doctor’s instructions for oral medication, such as metoprolol, bisoprolol and so on. If the patient’s symptoms are obvious, oral medication can be prescribed, such as metoprolol, bisoprolol, etc. If the condition further aggravates, cardiac radiofrequency ablation may be needed. 3. Intercostal neuralgia: Intercostal nerve due to infection, trauma and other causes of paroxysmal or persistent band-like distribution of chest pain, if caused by viral infections, need to comply with the doctor’s prescription of antiviral therapy, such as acyclovir, ganciclovir and so on, if the pain is intolerable, can be compliant with the doctor’s prescription of carbamazepine, Prevacid, and other pain-relieving treatments. In addition, digestive diseases such as reflux esophagitis, bile heart syndrome, respiratory diseases such as pleurisy, herpes zoster, etc., may also cause the above symptoms, and it is recommended to go to the hospital in time, so that the diagnosis can be clarified as soon as possible and the treatment can be tailored to the cause of the disease.