The quadrivalent HPV vaccine is suitable for women between the ages of 20 and 45 years old to prevent four types of HPV infections, including HPV16, HPV18, HPV6 and HPV11. The quadrivalent HPV vaccine not only prevents most cervical cancers, but also prevents vulvar, vaginal and perianal warts caused by HPV6 and HPV11. The quadrivalent HPV vaccine not only prevents most cervical cancers, but also prevents genital, vaginal, and perianal condyloma. Therefore, the quadrivalent HPV vaccine has a broader preventive effect against HPV infection than the bivalent HPV vaccine. The quadrivalent HPV vaccine requires three doses, one at month 0, one at month 2, and one at month 6.