Feeling leg pain after taking antihypertensive drugs should not be caused by the drugs, but may be caused by other drugs, such as statins. The more common antihypertensive drugs, including diuretics, sartans, prilosec, diphenhydramine, and lorazepam, mainly lower blood pressure by dilating blood vessels and do not cause leg pain. However, hypertensive patients often also need to take statin drugs to control blood lipids, such as pravastatin, resuvastatin, etc., after the use of the drug may produce certain adverse reactions, for example, lead to elevated liver enzymes or the impact on the muscles, the patient may have thigh pain and other symptoms. Feeling foot pain after taking antihypertensive drugs, should pay attention to rest and drink more water to promote metabolism, if the symptoms continue to be unrelieved, should consult a doctor in a timely manner, to identify the cause of the problem, and then targeted treatment or therapy.