The more Metronidazole Buccal Tablets are contained, the more painful they become, which may be related to the normal progression of the disease itself or to an adverse reaction to the drug. 1. Metronidazole buccal tablets is an anti-anaerobic drug, which has a killing effect on specialized anaerobic bacteria, so it is suitable for the treatment of gingivitis, periodontitis, pericoronitis and oral ulcers. 2. The more the drug is used, the more pain it contains may be related to the disease itself, that is, the indications of the disease in the normal course of the disease, itself may become more and more painful, such as acute pulpitis resulting in increased pressure on the pulp cavity, it will become more and more painful, at this time the use of metronidazole is almost ineffective. 3. In addition to the occasional dry mouth during treatment with drugs, mucosal irritation and other allergic reactions, long-term use can cause taste changes, generally disappear after stopping the drug, so the use of the drug after the more contained the more pain may also be related to adverse drug reactions. Note that contraindications include hypersensitivity to the product, patients with active central nervous system disorders, pregnant and lactating women. Alcohol-related beverages should not be consumed during the medication. Specific medication should be carried out under the guidance of a specialist, and should not be used without authorization.