Depression in the gastrointestinal reaction, depression is a heart disorder disease, ordinary patients will be manifested as emotional depression, reduced interest, reduced thinking, speech and movement are very little, will affect the patient’s learning and work. When suffering from depression, it can lead to abnormal secretion of various types of hormones in the brain, thus affecting the function of the gastrointestinal tract, and because of depression, it can also lead to dysfunction of the nerves of the internal organs, that is to say, it is often said that the patient may suffer from gastrointestinal dysfunction. Therefore, patients may experience abdominal distension, epigastric pain, precordial discomfort, boring pain, dyspepsia, intestinal cramps, abdominal pain, constipation, and diarrhea, and other gastrointestinal discomforts. And the patient has these uncomfortable symptoms, may be after a variety of tests, including gastroscopy enteroscopy, abdominal CT and other tests, did not find a significant organic lesions, in fact, this is the spirit of physical symptoms caused by the aggravation of the brain, that is, is often referred to as the brain-gut axis changes. In addition due to depression patients will also take some depression drugs, these drugs will also have an impact on the gastrointestinal nerves, affecting the function of the gastrointestinal tract.