Uric acid 440 μmol/L and creatinine 108 μmol/L are usually not too serious. Uric acid is a product of purine metabolism and creatinine is a nitrogenous metabolite, both of which are excreted by the kidneys. Clinically, the non-same day twice fasting blood uric acid > 420umol / L is often called hyperuricemia; normal adult creatinine value, men for 53 ~ 106umol / L, women for 44 ~ 97umol / L. If the patient consumes a lot of seafood, meat and other foods before the examination, the blood uric acid and blood creatinine levels can be elevated, which is usually seen in physiological conditions, usually not serious, and most of them can be relieved after removing the triggers. Uric acid 440 μmol / L, blood creatinine 108 μmol / L can also be seen in high uric acid kidney damage, acute and chronic renal failure, hyperuricemia and other pathological factors. At present, the level of uric acid and creatinine is slightly high, is not too serious, but need to pay attention to, suggest that the patient timely medical treatment, follow the doctor’s instructions to improve the relevant examination to clarify the cause of the disease, early detection and early diagnosis and early treatment is crucial. If the blood uric acid and creatinine levels are abnormal, it is recommended to go to a specialized hospital in time, standardize the treatment under the guidance of the doctor, and pay attention to regular review.