The normal value of serum chloride is 95-105mmol/L, and the results may vary according to different instruments. The main reasons for high serum chlorine include blood concentration, decreased excretion, hypoproteinemia, compensatory increase, increased absorption, excessive intake, etc. Consultation with a specialist is recommended.
1. Concentration of blood: high blood chloride is often caused by loss of water and concentration of blood, such as frequent vomiting, diarrhea, and profuse sweating.
2. Decreased excretion: Decreased excretion of blood chlorine often caused by certain diseases, such as oliguria in acute or chronic renal failure, cardiac insufficiency, ureteral or urethral obstruction.
3. Hypoproteinemia: certain renal diseases excrete too much urinary protein, plasma protein decreases, which can increase blood chlorine.
4. compensatory increase: respiratory alkalosis, often over-breathing, excessive carbon dioxide, blood chlorine compensatory increase.
5. Increased absorption: long-term application of glucocorticoids or Cushing’s syndrome can cause hyperadrenocorticism, so that the renal tubular absorption of sodium chloride increases.
6. Excessive intake: Eating or intravenous supplementation of large amounts of chlorine-containing substances, such as sodium chloride.
High serum chloride requires prompt clarification of the cause and active diagnosis and treatment.